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Clinicopathological Proficiency in the Diagnosis of Kaposi's Sarcoma
Author
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-30
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
The prevalence of Kaposi’s sarcoma (KS), an AIDS-defining illness, has increased in parallel with the HIV/AIDS epidemic.
The presence of violaceous skin lesions should raise suspicion of KS.
However, especially on dark skin, KS mimics a variety of non-KS skin conditions.
Histologically, there is a wide range of expressions of KS and a large number of mimickers.
For all these reasons, a HHV-8 immunohistochemically biopsy-proven diagnosis of KS should be the gold standard.
Methods.
Prospective study of 490 consecutive skin biopsies from the general community in the Limpopo Province of South Africa, from April 2010 through December 2011.
Results.
The clinical discordance rate (over-/underdiagnosis of KS) was 30.5%; the histological discordance rate was 9.2%.
Conclusion.
Because of the magnitude of diagnostic error, both clinical and histological, all clinical lesions suspicious of KS should be biopsied and HHV-8 LAN-1 immunophenotyped.
American Psychological Association (APA)
van Bogaert, Louis-Jacques. 2012. Clinicopathological Proficiency in the Diagnosis of Kaposi's Sarcoma. ISRN AIDS،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-481236
Modern Language Association (MLA)
van Bogaert, Louis-Jacques. Clinicopathological Proficiency in the Diagnosis of Kaposi's Sarcoma. ISRN AIDS No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-481236
American Medical Association (AMA)
van Bogaert, Louis-Jacques. Clinicopathological Proficiency in the Diagnosis of Kaposi's Sarcoma. ISRN AIDS. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-481236
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481236