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A Study to Compare the Analgesic Efficacy of Intrathecal Bupivacaine Alone with Intrathecal Bupivacaine Midazolam Combination in Patients Undergoing Elective Infraumbilical Surgery
Joint Authors
Ghosh, Kakali
Chattopadhyay, Anirban
Pal, Sugata
Maitra, Souvik
Layek, Amitava
Bhattacharjee, Sulagna
Sen, Suvadeep
Source
Anesthesiology Research and Practice
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-15
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Spinal anaesthesia, which is one of the techniques for infraumbilical surgeries, is most commonly criticized for limited duration of postoperative analgesia.
Several adjuvants have been tried along with local anesthetic for prolonging the duration of analgesia.
In this study, we have observed the effect of midazolam as an adjuvant in patients undergoing infraumbilical surgery.
In this prospective, randomized, double blinded, and parallel group and open label study of 90 adult patients aged 18–60 years, of American Society of Anaesthesiologists (ASA) status I and II, scheduled for elective infraumbilical surgery, were randomly allocated in two groups.
Each patient in group “B” received hyperbaric bupivacaine 12.5 mg along with 0.4 mL of normal saline in the subarachnoid block, and patients of group “BM” received 12.5 mg hyperbaric bupivacaine along with preservative free midazolam 0.4 mL (2 mg).
We found that use of midazolam as adjuvant with the local anesthetic in spinal anaesthesia significantly increases the duration of analgesia (median 320 min versus 220 min) and motor block (median 255 min versus 195 min) but decreases the incidence of postoperative nausea-vomiting (PONV).
American Psychological Association (APA)
Chattopadhyay, Anirban& Maitra, Souvik& Sen, Suvadeep& Bhattacharjee, Sulagna& Layek, Amitava& Pal, Sugata…[et al.]. 2013. A Study to Compare the Analgesic Efficacy of Intrathecal Bupivacaine Alone with Intrathecal Bupivacaine Midazolam Combination in Patients Undergoing Elective Infraumbilical Surgery. Anesthesiology Research and Practice،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-481277
Modern Language Association (MLA)
Chattopadhyay, Anirban…[et al.]. A Study to Compare the Analgesic Efficacy of Intrathecal Bupivacaine Alone with Intrathecal Bupivacaine Midazolam Combination in Patients Undergoing Elective Infraumbilical Surgery. Anesthesiology Research and Practice No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-481277
American Medical Association (AMA)
Chattopadhyay, Anirban& Maitra, Souvik& Sen, Suvadeep& Bhattacharjee, Sulagna& Layek, Amitava& Pal, Sugata…[et al.]. A Study to Compare the Analgesic Efficacy of Intrathecal Bupivacaine Alone with Intrathecal Bupivacaine Midazolam Combination in Patients Undergoing Elective Infraumbilical Surgery. Anesthesiology Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-481277
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481277