Aging Phenotypes of Common Marmosets (Callithrix jacchus)
Joint Authors
Davis, Kenneth
Dobek, Georgina
Ross, Corinna N.
Tardif, Suzette D.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-04
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Pharmacy, Health & Medical Sciences
Abstract EN
Characterizing the phenotypic changes associated with aging in a short-lived primate is necessary in order to develop better translational models for human health, aging, and disease research.
A population of conventionally housed marmoset monkeys was assessed to determine if phenotypes of body composition, hematology, and morphometrical measures were associated with age or risk of death.
We found that the cause of mortality in older marmosets was more likely to be due to cardiac and chronic kidney disease than in younger marmosets.
Older marmosets have decreased fat mass, morphometric measures, and serum albumin.
Older marmosets are more likely to show a modified posture while at rest and this modified posture was significantly associated with an increased risk of imminent death.
These assessments provide an initial definition of aged health in marmosets and a base for future translational aging research with this species.
American Psychological Association (APA)
Ross, Corinna N.& Davis, Kenneth& Dobek, Georgina& Tardif, Suzette D.. 2012. Aging Phenotypes of Common Marmosets (Callithrix jacchus). Journal of Aging Research،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-481279
Modern Language Association (MLA)
Ross, Corinna N.…[et al.]. Aging Phenotypes of Common Marmosets (Callithrix jacchus). Journal of Aging Research No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-481279
American Medical Association (AMA)
Ross, Corinna N.& Davis, Kenneth& Dobek, Georgina& Tardif, Suzette D.. Aging Phenotypes of Common Marmosets (Callithrix jacchus). Journal of Aging Research. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-481279
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481279