Ghrelin in Chronic Kidney Disease
Joint Authors
Source
International Journal of Peptides
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-03-17
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Patients with chronic kidney disease (CKD) often exhibit symptoms of anorexia and cachexia, which are associated with decreased quality of life and increased mortality.
Chronic inflammation may be an important mechanism for the development of anorexia, cachexia, renal osteodystrophy, and increased cardiovascular risk in CKD.
Ghrelin is a gastric hormone.
The biological effects of ghrelin are mediated through the growth hormone secretagogue receptor (GHSR).
The salutary effects of ghrelin on food intake and meal appreciation suggest that ghrelin could be an effective treatment for anorexic CKD patients.
In addition to its appetite-stimulating effects, ghrelin has been shown to possess anti-inflammatory properties.
The known metabolic effects of ghrelin and the potential implications in CKD will be discussed in this review.
The strength, shortcomings, and unanswered questions related to ghrelin treatment in CKD will be addressed.
American Psychological Association (APA)
Cheung, Wai W.& Mak, Robert H.. 2010. Ghrelin in Chronic Kidney Disease. International Journal of Peptides،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-481306
Modern Language Association (MLA)
Cheung, Wai W.& Mak, Robert H.. Ghrelin in Chronic Kidney Disease. International Journal of Peptides No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-481306
American Medical Association (AMA)
Cheung, Wai W.& Mak, Robert H.. Ghrelin in Chronic Kidney Disease. International Journal of Peptides. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-481306
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481306
