Anti-HPA-1b Mediated Posttransfusion Purpura : A Case Report
Joint Authors
Arewa, Oladimeji P.
Nahirniak, S.
Clarke, G.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-16
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Posttransfusion purpura (PTP) is an uncommon, but potentially fatal, transfusion reaction characterized by profound thrombocytopenia and bleeding.
PTP is caused by alloimmunization to human platelet specific antigens following blood component transfusion.
Although there is evidence of a wide serological spectrum of culprit antibodies implicated, Anti-human-platelet-antigen- (HPA-) 1a is the most common antibody in cases reported.
We report a case of posttransfusion purpura in an African American.
The patient was negative for HPA-1a antibodies, but anti-HPA-1b was identified with a platelet phenotype of HPA-1a/HPA-1a.
Although less common, HPA-1b antibody may be an important consideration in posttransfusion purpura diagnosed in patients of African descent.
American Psychological Association (APA)
Arewa, Oladimeji P.& Nahirniak, S.& Clarke, G.. 2014. Anti-HPA-1b Mediated Posttransfusion Purpura : A Case Report. Case Reports in Medicine،Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-481399
Modern Language Association (MLA)
Arewa, Oladimeji P.…[et al.]. Anti-HPA-1b Mediated Posttransfusion Purpura : A Case Report. Case Reports in Medicine No. 2013 (2013), pp.1-3.
https://search.emarefa.net/detail/BIM-481399
American Medical Association (AMA)
Arewa, Oladimeji P.& Nahirniak, S.& Clarke, G.. Anti-HPA-1b Mediated Posttransfusion Purpura : A Case Report. Case Reports in Medicine. 2014. Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-481399
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481399