Application of Scutellariae radix, Gardeniae fructus, and Probiotics to Prevent Salmonella enterica Serovar Choleraesuis Infection in Swine
Joint Authors
Chiou, Ming-Tang
Su, Chiu-Hsian
Chen, Daniel S.
Chang, Chiung-Hung
Hsu, Yuan-Man
Chen, Yueh-Sheng
Tsai, Chin-En
Yu, Bi
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-26
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Salmonella enterica serovar Choleraesuis, a host-adapted pathogen of swine, usually causes septicemia.
Lactic acid bacteria (LAB) strains have been widely studied in recent years for their probiotic properties.
In this study, a mouse infection model first screened for potential agents against infection, then a pig infection model evaluated effects of LAB strains and herbal plants against infection.
Scutellariae radix (SR) and Gardeniae fructus (GF) showed abilities to reduce bacteria shedding and suppressing serum level of TNF-α induced by infection in swine.
Bioactivities of SR and GF were enhanced by combining with LAB strains, which alone could speed up the bacteria elimination time in feces and boost immunity of infected pigs.
Baicalein and genipin exhibited stronger cytotoxicity than baicalin and geniposide did, as well as prevent Salmonella from invading macrophages.
Our study suggests LAB strains as exhibiting multiple functions: preventing infection, enhancing immunity to prepare host defenses against further infection, and adjusting intestinal microbes’ enzymatic activity in order to convert herbal compounds to active compounds.
The SR/GF-LAB strain mixture holds potential infection-prevention agents supplied as feed additives.
American Psychological Association (APA)
Chang, Chiung-Hung& Chen, Yueh-Sheng& Chiou, Ming-Tang& Su, Chiu-Hsian& Chen, Daniel S.& Tsai, Chin-En…[et al.]. 2013. Application of Scutellariae radix, Gardeniae fructus, and Probiotics to Prevent Salmonella enterica Serovar Choleraesuis Infection in Swine. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-481414
Modern Language Association (MLA)
Chang, Chiung-Hung…[et al.]. Application of Scutellariae radix, Gardeniae fructus, and Probiotics to Prevent Salmonella enterica Serovar Choleraesuis Infection in Swine. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-481414
American Medical Association (AMA)
Chang, Chiung-Hung& Chen, Yueh-Sheng& Chiou, Ming-Tang& Su, Chiu-Hsian& Chen, Daniel S.& Tsai, Chin-En…[et al.]. Application of Scutellariae radix, Gardeniae fructus, and Probiotics to Prevent Salmonella enterica Serovar Choleraesuis Infection in Swine. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-481414
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481414