Dyssynchrony Assessment with Tissue Doppler Imaging and Regional Volumetric Analysis by 3D Echocardiography Do Not Predict Long-Term Response to Cardiac Resynchronization Therapy
Joint Authors
al-Ahmad, Amin
Wang, Paul
Kuppahally, Suman S.
Liang, David
Vagelos, Randall
Hsia, Henry
Fowler, Michael B.
Source
Cardiology Research and Practice
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-12-22
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Currently there are no reliable predictors of response to cardiac resynchronization therapy (CRT) before implantation.
We compared pre-CRT left ventricular (LV) dyssynchrony by tissue Doppler imaging (TDI) and regional volumetric analysis by 3-dimensional transthoracic echocardiography (3DTTE) in predicting response to CRT.
Methods.
Thirty-eight patients (79% nonischemic cardiomyopathy) with symptomatic heart failure who underwent CRT were enrolled.
Clinical and echocardiographic responses were defined as improvement in one NYHA class and reduction in LV end-systolic volume by ≥15% respectively.
Functional status was assessed by Minnesota Living with Heart Failure questionnaire and 6-minute walk distance.
Results.
In 33 patients, after CRT for 7.86 ± 2.27 months, there were 24 (73%) clinical and 19 (58%) echocardiographic responders.
Functional parameters, LV dimensions, volumes and synchrony by TDI and 3DTTE improved significantly in responders.
There was no difference in the number of responders and nonresponders when cut-off values for dyssynchrony by different measurements validated in other trials were applied.
Area under receiver-operating-characteristic curve ranged from 0.4 to 0.6.
Conclusion.
CRT improves clinical and echocardiographic parameters in patients with systolic heart failure.
The dyssynchrony measurements by TDI and 3DTTE are not comparable and are unable to predict response to CRT.
American Psychological Association (APA)
Kuppahally, Suman S.& Fowler, Michael B.& Vagelos, Randall& Wang, Paul& al-Ahmad, Amin& Hsia, Henry…[et al.]. 2010. Dyssynchrony Assessment with Tissue Doppler Imaging and Regional Volumetric Analysis by 3D Echocardiography Do Not Predict Long-Term Response to Cardiac Resynchronization Therapy. Cardiology Research and Practice،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-481438
Modern Language Association (MLA)
Kuppahally, Suman S.…[et al.]. Dyssynchrony Assessment with Tissue Doppler Imaging and Regional Volumetric Analysis by 3D Echocardiography Do Not Predict Long-Term Response to Cardiac Resynchronization Therapy. Cardiology Research and Practice No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-481438
American Medical Association (AMA)
Kuppahally, Suman S.& Fowler, Michael B.& Vagelos, Randall& Wang, Paul& al-Ahmad, Amin& Hsia, Henry…[et al.]. Dyssynchrony Assessment with Tissue Doppler Imaging and Regional Volumetric Analysis by 3D Echocardiography Do Not Predict Long-Term Response to Cardiac Resynchronization Therapy. Cardiology Research and Practice. 2010. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-481438
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481438