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Short Communication : Some Observations on the Role of Bradykinin in Immunity to Teladorsagia circumcincta in Sheep
Author
Source
Journal of Parasitology Research
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-23
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Bradykinin is a physiologically active peptide involved in vasodilation and smooth muscle contraction and is previously shown to be increased in gastrointestinal mucus during nematode challenge in sheep.
Here, it is shown that bradykinin in the abomasum is positively correlated with both mast cells and globule leukocytes in the abomasum, and that all three of these parameters are negatively associated with numbers of adult Teladorsagia circumcincta during the challenge of immune sheep.
It is suggested that bradykinin either stimulates the degranulation of mast cells, or is released during this degranulation process, or both.
Multiple regression showed that almost 60% of the variation of in adult T.
circumcincta could be explained by two variables, bradykinin and T.
circumcincta—specific IgG1 in plasma.
This provides further evidence that bradykinin may be a mechanism of protective immunity in sheep, although its involvement in asthma and other allergic disorders raises questions about its role in unwanted immunopathology.
American Psychological Association (APA)
Williams, Andrew R.. 2012. Short Communication : Some Observations on the Role of Bradykinin in Immunity to Teladorsagia circumcincta in Sheep. Journal of Parasitology Research،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-481480
Modern Language Association (MLA)
Williams, Andrew R.. Short Communication : Some Observations on the Role of Bradykinin in Immunity to Teladorsagia circumcincta in Sheep. Journal of Parasitology Research No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-481480
American Medical Association (AMA)
Williams, Andrew R.. Short Communication : Some Observations on the Role of Bradykinin in Immunity to Teladorsagia circumcincta in Sheep. Journal of Parasitology Research. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-481480
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481480