Indeterminate Cell Histiocytosis in Association with Acute Myeloid Leukemia
Joint Authors
Pereira, Teresa
Duarte, Maria da Luz
Pardal, Fernando
Ventura, Filipa
Marques, Herlander
Brito, Celeste
Source
Dermatology Research and Practice
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-21
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Indeterminate cell histiocytosis (ICH) is a rare proliferative disorder, in which the predominant cells share morphologic and immunophenotypic features from both Langerhans and non-Langerhans cell histiocytosis.
We describe a 62-year-old man presenting a 2-month history of firm nodular lesions on the upper lip.
Histopathology, immunohistochemical, and ultrastructural analysis showed typical findings of ICH.
The patient was treated with thalidomide and almost complete regression of the lesions was reached within 7 months.
Nevertheless, one month after remission, he developed an acute myeloid leukemia of the subtype monocytic leukemia (M5).
The patient's condition rapidly worsened and he died due to a respiratory failure four weeks later.
We present this case because apart of being rare it joins the effectiveness of thalidomide and the association with an acute monocytic leukemia.
A review of the literature is made.
American Psychological Association (APA)
Ventura, Filipa& Pereira, Teresa& Duarte, Maria da Luz& Marques, Herlander& Pardal, Fernando& Brito, Celeste. 2010. Indeterminate Cell Histiocytosis in Association with Acute Myeloid Leukemia. Dermatology Research and Practice،Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-481484
Modern Language Association (MLA)
Ventura, Filipa…[et al.]. Indeterminate Cell Histiocytosis in Association with Acute Myeloid Leukemia. Dermatology Research and Practice No. 2010 (2010), pp.1-4.
https://search.emarefa.net/detail/BIM-481484
American Medical Association (AMA)
Ventura, Filipa& Pereira, Teresa& Duarte, Maria da Luz& Marques, Herlander& Pardal, Fernando& Brito, Celeste. Indeterminate Cell Histiocytosis in Association with Acute Myeloid Leukemia. Dermatology Research and Practice. 2010. Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-481484
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481484