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Phenotype and Metabolic Disorders in Polycystic Ovary Syndrome
Joint Authors
Stopińska-Głuszak, Urszula
Głuszak, Olgierd
Snochowska, Hanna
Dębski, Romuald
Kapuścińska, Renata
Glinicki, Piotr
Zgliczyński, Wojciech
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-29
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The polycystic ovary syndrome (PCOS) is one of the most frequent endocrinopathies in women.
Its incidence is assessed at 6–8% of the female population in the reproductive age.
It is characterised by oligomenorrhea (Oligo), hyperandrogenism (HA), and the presence of polycystic ovaries (PCOs).
Carbohydrate and lipid metabolism is being disturbed in many women with PCOS.
The pathogenesis of PCOS is still unexplained.
Following the main criteria of diagnosis (Rotterdam Consensus 2003), Dewailly, Welt and Pehlivanov divided the patients with PCOS into 4 phenotype groups: A, B, C, and D.
In our studies of 93 patients with PCOS, we found (1) the most frequent appearance (60,2%) of the phenotype A [Oligo + HA + PCO]; (2) an increased androstenedione concentration in a group with HA (A, B, C); (3) an increased HOMA-β and insulin concentration after 30 min an oral 75 g glucose tolerance test (OGTT) in a group of obese women with BMI>30 kg/m2; (4) high levels of total testosterone, total cholesterol, and LDL cholesterol concentrations in a group A with classic phenotype of PCOS: Oligo + HA + PCO—increasing the risk of development of cardiovascular diseases, type 2 diabetes, or metabolic syndrome.
The average androstenedione concentrations could be a good diagnostic and prognostic parameter.
American Psychological Association (APA)
Głuszak, Olgierd& Stopińska-Głuszak, Urszula& Glinicki, Piotr& Kapuścińska, Renata& Snochowska, Hanna& Zgliczyński, Wojciech…[et al.]. 2012. Phenotype and Metabolic Disorders in Polycystic Ovary Syndrome. ISRN Endocrinology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-481537
Modern Language Association (MLA)
Głuszak, Olgierd…[et al.]. Phenotype and Metabolic Disorders in Polycystic Ovary Syndrome. ISRN Endocrinology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-481537
American Medical Association (AMA)
Głuszak, Olgierd& Stopińska-Głuszak, Urszula& Glinicki, Piotr& Kapuścińska, Renata& Snochowska, Hanna& Zgliczyński, Wojciech…[et al.]. Phenotype and Metabolic Disorders in Polycystic Ovary Syndrome. ISRN Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-481537
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481537