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The Usefulness of Homeostatic Measurement Assessment-Insulin Resistance (HOMA-IR) for Detection of Glucose Intolerance in Thai Women of Reproductive Age with Polycystic Ovary Syndrome
Joint Authors
Tanmahasamut, Prasong
Indhavivadhana, Suchada
Leerasiri, Pichai
Dangrat, Chongdee
Rattanachaiyanont, Manee
Techatraisak, Kitirat
Wongwananuruk, Thanyarat
Angsuwathana, Surasak
Source
International Journal of Endocrinology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objectives.
To study the cut-off point of Homeostatic Measurement Assessment-Insulin Resistance (HOMA-IR) as a screening test for detection of glucose intolerance in Thai women with polycystic ovary syndrome (PCOS).
Study Design.
Cross-sectional study.
Setting.
Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital.
Subject.
Two hundred and fifty Thai PCOS women who attended the Gynecologic Endocrinology Unit, during May 2007 to January 2009.
Materials and Methods.
The paitents were interviewed and examined for weight, height, waist circumference, and blood pressure.
Venous blood samples were drawn twice, one at 12-hour fasting and the other at 2 hours after glucose loading.
Results.
The prevalence of glucose intolerance in Thai PCOS women was 20.0%.
The mean of HOMA-IR was 3.53 ± 7.7.
Area under an ROC curve for HOMA-IR for detecting glucose intolerance was 0.82.
Using the cut-off value of HOMA-IR >2.0, there was sensitivity at 84.0%, specificity at 61.0%, positive predictive value at 35.0%, negative predictive value at 93.8%, and accuracy at 65.6%.
Conclusion.
HOMA-IR >2.0 was used for screening test for glucose intolerance in Thai PCOS women.
If the result was positive, a specific test should be done to prove the diagnosis.
American Psychological Association (APA)
Wongwananuruk, Thanyarat& Rattanachaiyanont, Manee& Leerasiri, Pichai& Indhavivadhana, Suchada& Techatraisak, Kitirat& Angsuwathana, Surasak…[et al.]. 2012. The Usefulness of Homeostatic Measurement Assessment-Insulin Resistance (HOMA-IR) for Detection of Glucose Intolerance in Thai Women of Reproductive Age with Polycystic Ovary Syndrome. International Journal of Endocrinology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-481632
Modern Language Association (MLA)
Wongwananuruk, Thanyarat…[et al.]. The Usefulness of Homeostatic Measurement Assessment-Insulin Resistance (HOMA-IR) for Detection of Glucose Intolerance in Thai Women of Reproductive Age with Polycystic Ovary Syndrome. International Journal of Endocrinology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-481632
American Medical Association (AMA)
Wongwananuruk, Thanyarat& Rattanachaiyanont, Manee& Leerasiri, Pichai& Indhavivadhana, Suchada& Techatraisak, Kitirat& Angsuwathana, Surasak…[et al.]. The Usefulness of Homeostatic Measurement Assessment-Insulin Resistance (HOMA-IR) for Detection of Glucose Intolerance in Thai Women of Reproductive Age with Polycystic Ovary Syndrome. International Journal of Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-481632
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481632