Targeted Delivery of Nanomedicines
Author
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-10
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Pharmacy, Health & Medical Sciences
Pharmacology
Abstract EN
The role of targeting of the diseased region by a drug is emphasized.
The rationale for resorting to nanomaterials as drug carriers is explained.
A clear understanding of the biological environment, its degradation in diseased condition, and the interaction of the drug with it in normal condition and during illness lie at the core of successful drug delivery.
Passive and active drug targeting approaches are differentiated.
Commonly used drug targets, targeting ligands, and nanoscale systems are elaborated.
Mechanisms of internalization of nanomedicines and circumventing P-glycoprotein mediated resistance are outlined.
The paper presents an overview of the current scenario of targeted transportation of nanomedicines to the affected organ and suggests future research directions.
American Psychological Association (APA)
Kumar Khanna, Vinod. 2012. Targeted Delivery of Nanomedicines. ISRN Pharmacology،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-481659
Modern Language Association (MLA)
Kumar Khanna, Vinod. Targeted Delivery of Nanomedicines. ISRN Pharmacology No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-481659
American Medical Association (AMA)
Kumar Khanna, Vinod. Targeted Delivery of Nanomedicines. ISRN Pharmacology. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-481659
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481659