Treatment of Anxiety Disorders and Comorbid Alcohol Abuse with Buspirone in a Patient with Antidepressant-Induced Platelet Dysfunction : A Case Report
Joint Authors
Munshi, Tariq
Mazhar, Mir
Hassan, Tariq
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-12
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
The risk of abnormal bleeding with serotonin reuptake inhibitors has been known, but there is insufficient evidence base to guide pharmacological treatment of anxiety in patients with underlying haematological conditions.
The following case report is about a 50-year-old female with generalized anxiety disorder, social phobia, obsessive compulsive disorder, and alcohol abuse where pharmacological treatment of anxiety symptoms has been difficult as it would lead to bruising due to the patient’s underlying qualitative platelet dysfunction.
Treatment with venlafaxine, citalopram, escitalopram, and clomipramine resulted in improvement and anxiety symptoms, as well as reduction in alcohol use, but pharmacological treatment has to be discontinued because of bruising and hematomas.
In view of an active substance use disorder, benzodiazepines were avoided as a treatment option.
The patient’s anxiety symptoms and comorbid alcohol abuse responded well to pharmacological treatment with buspirone which gradually titrated up to a dose of 30 mg BID.
Patient was followed for around a six-month period while she was on buspirone before being discharged to family doctor’s care.
Buspirone is unlikely to have a significant effect on platelet serotonin transponder and could be an effective alternative for pharmacological treatment of anxiety in patients with a bleeding diathesis.
American Psychological Association (APA)
Mazhar, Mir& Hassan, Tariq& Munshi, Tariq. 2013. Treatment of Anxiety Disorders and Comorbid Alcohol Abuse with Buspirone in a Patient with Antidepressant-Induced Platelet Dysfunction : A Case Report. Case Reports in Psychiatry،Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-481784
Modern Language Association (MLA)
Mazhar, Mir…[et al.]. Treatment of Anxiety Disorders and Comorbid Alcohol Abuse with Buspirone in a Patient with Antidepressant-Induced Platelet Dysfunction : A Case Report. Case Reports in Psychiatry No. 2013 (2013), pp.1-3.
https://search.emarefa.net/detail/BIM-481784
American Medical Association (AMA)
Mazhar, Mir& Hassan, Tariq& Munshi, Tariq. Treatment of Anxiety Disorders and Comorbid Alcohol Abuse with Buspirone in a Patient with Antidepressant-Induced Platelet Dysfunction : A Case Report. Case Reports in Psychiatry. 2013. Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-481784
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481784