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Focal Therapy, Differential Therapy, and Radiation Treatment for Prostate Cancer
Joint Authors
Ennis, Ronald D.
Jain, Anudh K.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Focal and differential therapy represent an approach to improve the therapeutic ratio of prostate cancer treatments.
This concept is a shift from treating the whole gland to intensely treating the portion of the gland that contains significant tumor.
However, there are many challenges in the move towards focal approaches.
Defining which patients are suitable candidates for focal therapy approaches is an area of significant controversy, and it is likely that additional data from imaging or detailed biopsy methods is needed in addition to traditional risk factors.
A number of methods have been suggested, and imaging with multiparametric MRI and transperineal template mapping biopsy have shown promise.
The approach of differential therapy where the entire prostate is treated to a lower intensity and the tumor areas to high intensity is also discussed in detail.
Radiation therapy is a well suited modality for the delivery of differential therapy.
Data in the literature using external beam radiation, high dose rate brachytherapy, and low-dose rate brachytherapy for differential therapy are reviewed.
Preliminary results are encouraging, and larger studies and randomized controlled trials are needed to validate this approach.
American Psychological Association (APA)
Jain, Anudh K.& Ennis, Ronald D.. 2012. Focal Therapy, Differential Therapy, and Radiation Treatment for Prostate Cancer. Advances in Urology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-481848
Modern Language Association (MLA)
Jain, Anudh K.& Ennis, Ronald D.. Focal Therapy, Differential Therapy, and Radiation Treatment for Prostate Cancer. Advances in Urology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-481848
American Medical Association (AMA)
Jain, Anudh K.& Ennis, Ronald D.. Focal Therapy, Differential Therapy, and Radiation Treatment for Prostate Cancer. Advances in Urology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-481848
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481848