Bone Mineral Density in Thalassemia Major Patients from Antalya, Turkey
Joint Authors
Aslan, Ibrahim
Dorak, Cengaver
Ozsancak, Ahmet
Canatan, Duran
Oguz, Nurgul
Kacar, Gulizar
Cosan, Ruya
Balta, Nihal
Source
International Journal of Endocrinology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-20
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Aim.
We assessed the bone mineral density and related parameters in nine adults, thirty-eight pubertal, prepubertal totally forty-seven patients with thalassemia major living in Antalya, Turkey.
Materials and Methods.
We measured height and pubertal staging in last five years by six-month intervals.
Average ferritin and hemoglobin concentrations were calculated for last three years.
The levels of hydroxyproline, calcium, phosphorus, and creatinine were measured in 24 h urine, and those of parathormone, IGF 1, osteocalcine, alkaline phosphatase, calcium, ionized calcium, magnesium, phosphorus, creatine, blood glucose, thyroid stimulating hormone, alanine transaminase, and aspartate transaminase were determined in serum, and also the bone mineral density was measured.
Results.
The average L1–L4 bone mass density was 27.1±10.1 g cm−2; the average bone mineral content was 0.65 ± 0.11 g.
of the patients with a Z-score under 2.5.
A moderate relationship was found between the bone mass density age and height.
Subjects in low pubertal staging and short stature (<3% percentile) have significantly lower bone mass densities P<0.001.
Conclusion.
he prevalence of osteoporosis is high in patients with thalassemia major, possibly related to delayed puberty.
American Psychological Association (APA)
Aslan, Ibrahim& Canatan, Duran& Balta, Nihal& Kacar, Gulizar& Dorak, Cengaver& Ozsancak, Ahmet…[et al.]. 2012. Bone Mineral Density in Thalassemia Major Patients from Antalya, Turkey. International Journal of Endocrinology،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-481863
Modern Language Association (MLA)
Aslan, Ibrahim…[et al.]. Bone Mineral Density in Thalassemia Major Patients from Antalya, Turkey. International Journal of Endocrinology No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-481863
American Medical Association (AMA)
Aslan, Ibrahim& Canatan, Duran& Balta, Nihal& Kacar, Gulizar& Dorak, Cengaver& Ozsancak, Ahmet…[et al.]. Bone Mineral Density in Thalassemia Major Patients from Antalya, Turkey. International Journal of Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-481863
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481863