Laryngeal Synovial Sarcoma : A Rare Clinical Entity
Joint Authors
Bova, Ron
Edwards, Melanie
Saxby, Clair
Source
Case Reports in Otolaryngology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-08
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Introduction.
Synovial sarcomas (SS) are aggressive malignant soft tissue tumours that are thought to arise from pluripotent mesenchymal cells.
Clinical Report.
A 20-year-old male presented with an acute onset of respiratory stridor.
Computer tomography scanning confirmed a mass arising from the left supraglottic larynx and an emergency tracheostomy was performed.
A diagnosis of biphasic synovial sarcoma was formed.
A total laryngectomy and left hemithyroidectomy was performed in conjunction with a left modified radical neck dissection.
The patient received adjuvant chemotherapy followed by a course of radiotherapy and remains alive and disease free at 18 months after treatment.
Discussion.
Prognosis for patients with SS is related to primary tumour extent, grade, and size.
The presence of the diagnostic translocation, t(X;18), is being targeted and hopefully will lead to the development of new therapeutics (Guadagnolo et al., 2007).
Conclusion.
Laryngeal SS remains a rare and poorly understood entity.
A multidisciplinary approach to treatment is essential and long-term followup is imperative.
American Psychological Association (APA)
Saxby, Clair& Bova, Ron& Edwards, Melanie. 2013. Laryngeal Synovial Sarcoma : A Rare Clinical Entity. Case Reports in Otolaryngology،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-482239
Modern Language Association (MLA)
Saxby, Clair…[et al.]. Laryngeal Synovial Sarcoma : A Rare Clinical Entity. Case Reports in Otolaryngology No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-482239
American Medical Association (AMA)
Saxby, Clair& Bova, Ron& Edwards, Melanie. Laryngeal Synovial Sarcoma : A Rare Clinical Entity. Case Reports in Otolaryngology. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-482239
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482239