Biomarkers in Exhaled Breath Condensate and Serum of Chronic Obstructive Pulmonary Disease and Non-Small-Cell Lung Cancer
Joint Authors
Source
International Journal of Chronic Diseases
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-04
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Chronic obstructive pulmonary disease (COPD) and lung cancer are leading causes of deaths worldwide which are associated with chronic inflammation and oxidative stress.
Lung cancer, in particular, has a very high mortality rate due to the characteristically late diagnosis.
As such, identification of novel biomarkers which allow for early diagnosis of these diseases could improve outcome and survival rate.
Markers of oxidative stress in exhaled breath condensate (EBC) are examples of potential diagnostic markers for both COPD and non-small-cell lung cancer (NSCLC).
They may even be useful in monitoring treatment response.
In the serum, S100A8, S100A9, and S100A12 of the S100 proteins are proinflammatory markers.
They have been indicated in several inflammatory diseases and cancers including secondary metastasis into the lung.
It is highly likely that they not only have the potential to be diagnostic biomarkers for NSCLC but also prognostic indicators and therapeutic targets.
American Psychological Association (APA)
Lim, Mann Ying& Thomas, Paul S.. 2013. Biomarkers in Exhaled Breath Condensate and Serum of Chronic Obstructive Pulmonary Disease and Non-Small-Cell Lung Cancer. International Journal of Chronic Diseases،Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-482241
Modern Language Association (MLA)
Lim, Mann Ying& Thomas, Paul S.. Biomarkers in Exhaled Breath Condensate and Serum of Chronic Obstructive Pulmonary Disease and Non-Small-Cell Lung Cancer. International Journal of Chronic Diseases No. 2013 (2013), pp.1-15.
https://search.emarefa.net/detail/BIM-482241
American Medical Association (AMA)
Lim, Mann Ying& Thomas, Paul S.. Biomarkers in Exhaled Breath Condensate and Serum of Chronic Obstructive Pulmonary Disease and Non-Small-Cell Lung Cancer. International Journal of Chronic Diseases. 2013. Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-482241
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482241