Efficacy and Tolerability of Intramuscular Dexketoprofen in Postoperative Pain Management following Hernia Repair Surgery
Joint Authors
Shinde, J. V.
Dhorepatil, S.
Karmarkar, P. S.
Bhagat, H.
Erram, S. S.
Kolte, S. S.
Bhagtani, K.
Kamat, V. V.
Jamdade, P. T.
Irpatgire, R.
Porwal, A.
Shirure, P. A.
Source
Anesthesiology Research and Practice
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-12
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Objective.
To evaluate the safety and efficacy of intramuscular dexketoprofen for postoperative pain in patients undergoing hernia surgery.
Methodology.
Total 202 patients received single intramuscular injection of dexketoprofen 50 mg or diclofenac 50 mg postoperatively.
The pain intensity (PI) was self-evaluated by patients on VAS at baseline 1, 2, 4, 6, and 8 hours.
The efficacy parameters were number of responders, difference in PI (PID) at 8 hours, sum of analogue of pain intensity differences (SAPID), and onset and duration of analgesia.
Tolerability assessment was done by global evaluation and adverse events in each group.
Results.
Dexketoprofen showed superior efficacy in terms of number of responders (P=.007), PID at 8 hours (P=.02), and SAPID 0–8 hours (P<.0001).
It also showed faster onset of action (42 minutes) and longer duration of action (6.5 hours).
The adverse events were comparable in both groups.
Conclusion.
Single dose of dexketoprofen trometamol 50 mg given intramuscularly provided faster, better, and longer duration of analgesia in postoperative patients of hernia repair surgery than diclofenac 50 mg, with comparable safety.
American Psychological Association (APA)
Jamdade, P. T.& Porwal, A.& Shinde, J. V.& Erram, S. S.& Kamat, V. V.& Karmarkar, P. S.…[et al.]. 2011. Efficacy and Tolerability of Intramuscular Dexketoprofen in Postoperative Pain Management following Hernia Repair Surgery. Anesthesiology Research and Practice،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-482275
Modern Language Association (MLA)
Jamdade, P. T.…[et al.]. Efficacy and Tolerability of Intramuscular Dexketoprofen in Postoperative Pain Management following Hernia Repair Surgery. Anesthesiology Research and Practice No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-482275
American Medical Association (AMA)
Jamdade, P. T.& Porwal, A.& Shinde, J. V.& Erram, S. S.& Kamat, V. V.& Karmarkar, P. S.…[et al.]. Efficacy and Tolerability of Intramuscular Dexketoprofen in Postoperative Pain Management following Hernia Repair Surgery. Anesthesiology Research and Practice. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-482275
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482275