Severe Hypercholesterolemia : A Unique Presentation of Non-Hodgkin’s Lymphoma in a Patient with Neurofibromatosis Type 1
Joint Authors
Tsirlin, Yuriy
Chudy-Onwugaje, Kenechukwu
Anyadike, Nnaemeka
Mayer, Ira
Rahmani, Rabin
Source
Case Reports in Gastrointestinal Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-30
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
We report a case of non-Hodgkin’s lymphoma (NHL) with an unusual initial manifestation as severe hypercholesterolemia and obstructive jaundice in a patient with neurofibromatosis type 1 (NF 1).
NHL should be considered in the evaluation of obstructive jaundice alone or in combination with severe hypercholesterolemia.
Relief of biliary obstruction led to the resolution of hypercholesterolemia in our 59-year-old male patient, followed by doxorubicin-based chemotherapy for the underlying lymphoma.
NF 1 is a genetic condition that results from a defect in a tumor-suppressor gene and it is likely that this led to the development of NHL in our patient.
It is important that clinicians are familiar with the gastrointestinal manifestations of NF 1, especially its association with intra-abdominal malignancies, when treating patients with a personal or family history.
To the best of our knowledge, this is the first case of NHL presenting initially as severe hypercholesterolemia and it is also one of the few instances where NHL has been reported in association with NF 1.
American Psychological Association (APA)
Chudy-Onwugaje, Kenechukwu& Anyadike, Nnaemeka& Tsirlin, Yuriy& Mayer, Ira& Rahmani, Rabin. 2014. Severe Hypercholesterolemia : A Unique Presentation of Non-Hodgkin’s Lymphoma in a Patient with Neurofibromatosis Type 1. Case Reports in Gastrointestinal Medicine،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-482309
Modern Language Association (MLA)
Chudy-Onwugaje, Kenechukwu…[et al.]. Severe Hypercholesterolemia : A Unique Presentation of Non-Hodgkin’s Lymphoma in a Patient with Neurofibromatosis Type 1. Case Reports in Gastrointestinal Medicine No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-482309
American Medical Association (AMA)
Chudy-Onwugaje, Kenechukwu& Anyadike, Nnaemeka& Tsirlin, Yuriy& Mayer, Ira& Rahmani, Rabin. Severe Hypercholesterolemia : A Unique Presentation of Non-Hodgkin’s Lymphoma in a Patient with Neurofibromatosis Type 1. Case Reports in Gastrointestinal Medicine. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-482309
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482309