Innate Immune Sensors and Gastrointestinal Bacterial Infections
Joint Authors
Mukhopadhya, Indrani
Monie, Tom P.
Hold, Georgina L.
Source
Clinical and Developmental Immunology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-19
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The gastrointestinal microbiota is a major source of immune stimulation.
The interaction between host pattern-recognition receptors and conserved microbial ligands profoundly influences infection dynamics.
Identifying and understanding the nature of these interactions is a key step towards obtaining a clearer picture of microbial pathogenesis.
These interactions underpin a complex interplay between microbe and host that has far reaching consequences for both.
Here, we review the role of pattern recognition receptors in three prototype diseases affecting the stomach, the small intestine, and large intestine, respectively (Helicobacter pylori infection, Salmonella infection, and inflammatory bowel disease).
Specifically, we review the nature and impact of pathogen:receptor interactions, their impact upon pathogenesis, and address the relevance of pattern recognition receptors in the development of therapies for gastrointestinal diseases.
American Psychological Association (APA)
Hold, Georgina L.& Mukhopadhya, Indrani& Monie, Tom P.. 2011. Innate Immune Sensors and Gastrointestinal Bacterial Infections. Clinical and Developmental Immunology،Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-482344
Modern Language Association (MLA)
Hold, Georgina L.…[et al.]. Innate Immune Sensors and Gastrointestinal Bacterial Infections. Clinical and Developmental Immunology No. 2011 (2011), pp.1-11.
https://search.emarefa.net/detail/BIM-482344
American Medical Association (AMA)
Hold, Georgina L.& Mukhopadhya, Indrani& Monie, Tom P.. Innate Immune Sensors and Gastrointestinal Bacterial Infections. Clinical and Developmental Immunology. 2011. Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-482344
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482344