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Serum Leptin Concentration Positively Correlates with Body Weight and Total Fat Mass in Postmenopausal Japanese Women with Osteoarthritis of the Knee
Joint Authors
Matsumoto, Hideo
Iwamoto, Jun
Sato, Yoshihiro
Takeda, Tsuyoshi
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-01-24
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The objective of the present study was to identify factors correlated with the serum leptin concentration in women with knee OA.
Fifty postmenopausal Japanese women with knee OA (age: 50–88 years) were recruited in our outpatient clinic.
Plain radiographs of the knee were taken, and urine and blood samples were collected.
Dual-energy X-ray absorptiometry (DXA) scanning was performed for the whole body and lumbar spine, and factors correlated with the serum leptin concentration were identified.
A simple linear regression analysis showed that body weight, body mass index, whole-body bone mineral density (BMD), total fat mass, and total fat percentage, but not age, height, lumbar spine BMD, lean body mass, serum and urinary bone turnover markers, or the radiographic grade of knee OA, were significantly correlated with the serum leptin concentration.
A multiple regression analysis showed that among these factors, only body weight and total fat mass exhibited a significant positive correlation with the serum leptin concentration.
These results suggest that the serum leptin concentration might be related to increases in body weight and total fat mass, but not to BMD or bone turnover markers, in postmenopausal women with OA.
American Psychological Association (APA)
Iwamoto, Jun& Takeda, Tsuyoshi& Sato, Yoshihiro& Matsumoto, Hideo. 2011. Serum Leptin Concentration Positively Correlates with Body Weight and Total Fat Mass in Postmenopausal Japanese Women with Osteoarthritis of the Knee. Arthritis،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-482415
Modern Language Association (MLA)
Iwamoto, Jun…[et al.]. Serum Leptin Concentration Positively Correlates with Body Weight and Total Fat Mass in Postmenopausal Japanese Women with Osteoarthritis of the Knee. Arthritis No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-482415
American Medical Association (AMA)
Iwamoto, Jun& Takeda, Tsuyoshi& Sato, Yoshihiro& Matsumoto, Hideo. Serum Leptin Concentration Positively Correlates with Body Weight and Total Fat Mass in Postmenopausal Japanese Women with Osteoarthritis of the Knee. Arthritis. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-482415
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482415