Low Serum Magnesium Level Is Associated with Microalbuminuria in Chinese Diabetic Patients
Joint Authors
Xu, Yu
Xu, Min
Lu, Jieli
Huang, Xiaolin
Sun, Wanwan
Deng, Xinru
Sun, Jichao
Bi, Yufang
Xu, Baihui
Source
International Journal of Endocrinology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-26
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Whether serum magnesium deficiency is independently associated with the prevalence of microalbuminuria is still unclear.
The objective of the present study was to elucidate the association between serum magnesium and microalbuminuria in diabetic patients.
A cross-sectional study was conducted in 1829 diabetic subjects (aged ≥ 40 years) from Shanghai, China.
Subjects were divided into three groups according to serum magnesium tertiles.
A first-voided early-morning spot urine sample was obtained for urinary albumin-creatinine ratio (UACR) measurement.
Microalbuminuria was defined as 30 mg/g ≤ UACR < 300 mg/g.
Overall, 208 (11.37%) of the study population had microalbuminuria, with similar proportions in both genders (P=0.44).
The prevalence of microalbuminuria in tertile 1 of serum magnesium was higher than the prevalence in tertile 2 and tertile 3 (15.98%, 9.72%, and 8.46%, resp.; P for trend <0.0001).
After adjustment for age, sex, BMI, blood pressure, lipidaemic profile, HbA1c, eGFR, history of cardiovascular disease, HOMA-IR, antihypertensive and antidiabetic medication, and diabetes duration, we found that, compared with the subjects in tertile 3 of serum magnesium, those in tertile 1 had 1.85 times more likeliness to have microalbuminuria.
We concluded that low serum magnesium level was significantly associated with the prevalence of microalbuminuria in middle-aged and elderly Chinese.
American Psychological Association (APA)
Xu, Baihui& Sun, Jichao& Deng, Xinru& Huang, Xiaolin& Sun, Wanwan& Xu, Yu…[et al.]. 2013. Low Serum Magnesium Level Is Associated with Microalbuminuria in Chinese Diabetic Patients. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-482422
Modern Language Association (MLA)
Xu, Baihui…[et al.]. Low Serum Magnesium Level Is Associated with Microalbuminuria in Chinese Diabetic Patients. International Journal of Endocrinology No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-482422
American Medical Association (AMA)
Xu, Baihui& Sun, Jichao& Deng, Xinru& Huang, Xiaolin& Sun, Wanwan& Xu, Yu…[et al.]. Low Serum Magnesium Level Is Associated with Microalbuminuria in Chinese Diabetic Patients. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-482422
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482422