PEDF in Diabetic Retinopathy : A Protective Effect of Oxidative Stress
Joint Authors
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-10
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Diabetic retinopathy (DR) is a major cause of blindness in working age adults, and oxidative stress plays a vital role in the pathogenesis of DR.
Pigment-epithelium-derived factor (PEDF), a multifunctional protein, has shown to inhibit the development of DR by accumulating evidence.
This paper highlights the current understanding of probable mechanism about how PEDF blocks the deterioration of DR through its antioxidative properties and application prospects of PEDF as a novel therapeutic target in DR.
Gene therapy of PEDF is becoming more and more acceptable and will widely be applied to the actual treatment in the near future.
American Psychological Association (APA)
Zhu, Xiao-feng& Zou, Hai-dong. 2012. PEDF in Diabetic Retinopathy : A Protective Effect of Oxidative Stress. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-482424
Modern Language Association (MLA)
Zhu, Xiao-feng& Zou, Hai-dong. PEDF in Diabetic Retinopathy : A Protective Effect of Oxidative Stress. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-482424
American Medical Association (AMA)
Zhu, Xiao-feng& Zou, Hai-dong. PEDF in Diabetic Retinopathy : A Protective Effect of Oxidative Stress. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-482424
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482424