Previously Unreported Chromosomal Aberrations of t(3;3)(q29;q23), t(4;11)(q21;q23), and t(11;18)(q10;q10) in a Patient with Accelerated Phase Ph+ CML
Joint Authors
Undar, Levent
Salim, Ozan
Aydin, Cigdem
Cetin, Zafer
Berker Karauzum, Sibel
Yucel, Orhan Kemal
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-22
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Chronic myelogenous leukemia (CML) is a clonal hematological disorder, which is characterized by the presence of the classical or variant Philadelphia translocations.
During the progression to blastic phase of the disease secondary chromosomal abnormalities may emerge.
Such secondary chromosomal abnormalities are nonrandom, the more frequent ones being trisomy 8 and 19, supernumerary i(17q), and extra Philadelphia chromosomes.
Furthermore, a minor percentage of the patients may acquire different secondary chromosomal abnormalities including translocations between other chromosomes.
We report here a patient with Ph+ CML presenting secondary chromosomal abnormalities including t(4;11)(q21;q23), t(3;3)(q29;q23) and t(11;18)(q10;q10) during the course of CML progression.
American Psychological Association (APA)
Aydin, Cigdem& Cetin, Zafer& Salim, Ozan& Yucel, Orhan Kemal& Undar, Levent& Berker Karauzum, Sibel. 2014. Previously Unreported Chromosomal Aberrations of t(3;3)(q29;q23), t(4;11)(q21;q23), and t(11;18)(q10;q10) in a Patient with Accelerated Phase Ph+ CML. Case Reports in Genetics،Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-482553
Modern Language Association (MLA)
Aydin, Cigdem…[et al.]. Previously Unreported Chromosomal Aberrations of t(3;3)(q29;q23), t(4;11)(q21;q23), and t(11;18)(q10;q10) in a Patient with Accelerated Phase Ph+ CML. Case Reports in Genetics No. 2014 (2014), pp.1-3.
https://search.emarefa.net/detail/BIM-482553
American Medical Association (AMA)
Aydin, Cigdem& Cetin, Zafer& Salim, Ozan& Yucel, Orhan Kemal& Undar, Levent& Berker Karauzum, Sibel. Previously Unreported Chromosomal Aberrations of t(3;3)(q29;q23), t(4;11)(q21;q23), and t(11;18)(q10;q10) in a Patient with Accelerated Phase Ph+ CML. Case Reports in Genetics. 2014. Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-482553
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482553
