Polyvinyl Alcohol Hydrogel Irradiated and Acetalized for Osteochondral Defect Repair : Mechanical, Chemical, and Histological Evaluation after Implantation in Rat Knees
Joint Authors
Mariolani, J. R. L.
Bavaresco, V. P.
Rodrigues, A. A.
Batista, N. A.
Belangero, W. D.
Source
International Journal of Biomaterials
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-01
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Polyvinyl Alcohol (PVA) hydrogel plugs were implanted in artificial osteochondral defects on the trochlear groove of rat knees.
After 0, 3, 6, 12, and 24 weeks of followup, samples containing the implants were mechanically evaluated by creep indentation test, chemically, and histologically by optical microscopy.
The mechanical test pointed towards an increase of the implant creep modulus and the chemical analysis exhibited an increasing concentration of calcium and phosphorus within the implants over time.
Optical microscopy showed no foreign body reaction and revealed formation, differentiation, and maintenance of new tissue at the defect/implant interface.
The absence of implant wear indicated that the natural articular lubrication process was not disturbed by the implant.
The performance of the irradiated and acetalized PVA was considered satisfactory for the proposed application.
American Psychological Association (APA)
Batista, N. A.& Rodrigues, A. A.& Bavaresco, V. P.& Mariolani, J. R. L.& Belangero, W. D.. 2012. Polyvinyl Alcohol Hydrogel Irradiated and Acetalized for Osteochondral Defect Repair : Mechanical, Chemical, and Histological Evaluation after Implantation in Rat Knees. International Journal of Biomaterials،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-482609
Modern Language Association (MLA)
Batista, N. A.…[et al.]. Polyvinyl Alcohol Hydrogel Irradiated and Acetalized for Osteochondral Defect Repair : Mechanical, Chemical, and Histological Evaluation after Implantation in Rat Knees. International Journal of Biomaterials No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-482609
American Medical Association (AMA)
Batista, N. A.& Rodrigues, A. A.& Bavaresco, V. P.& Mariolani, J. R. L.& Belangero, W. D.. Polyvinyl Alcohol Hydrogel Irradiated and Acetalized for Osteochondral Defect Repair : Mechanical, Chemical, and Histological Evaluation after Implantation in Rat Knees. International Journal of Biomaterials. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-482609
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482609