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Central Precocious Puberty : Treatment with Triptorelin 11.25 mg
Joint Authors
Galluzzi, Fiorella
Baroncelli, Giampiero I.
Cappa, Marco
Russo, Gianni
Dati, Eleonora
Wasniewska, Malgorzata
Chiocca, Elena
Bertelloni, Silvano
Einaudi, Silvia
Cassio, Alessandra
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Background.
Few data are available on quarterly 11.25 mg GnRH analog treatment in central precocious puberty (CPP).
Aim.
To assess the efficacy of triptorelin 11.25 mg in children with CPP.
Patients.
17 patients (16 females) with CPP (7.9±0.9 years) were treated with triptorelin 11.25 mg/90 days.
Methods.
Gonadotropins, basal-, and GnRH-stimulated peak, gonadal steroids, and pubertal signs were assessed at preinclusion and at inclusion visit, 3 months, 6 months, and 12 months of treatment.
Results.
At 3, 6, and 12 months, all patients had suppressed LH peak (<3 IU/L after GnRH stimulation), as well as prepubertal oestradiol levels.
Mean LH peak values after GnRH test significantly decreased from 25.7±16.5 IU/L at baseline to 0.9±0.5 IU/L at M3 (P<0.0001); they did not significantly changed at M6 and M12.
Conclusions.
Triptorelin 11.25 mg/90 days efficiently suppressed the pituitary-gonadal axis in children with CPP from first administration.
American Psychological Association (APA)
Chiocca, Elena& Dati, Eleonora& Baroncelli, Giampiero I.& Cassio, Alessandra& Wasniewska, Malgorzata& Galluzzi, Fiorella…[et al.]. 2012. Central Precocious Puberty : Treatment with Triptorelin 11.25 mg. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-482701
Modern Language Association (MLA)
Chiocca, Elena…[et al.]. Central Precocious Puberty : Treatment with Triptorelin 11.25 mg. The Scientific World Journal No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-482701
American Medical Association (AMA)
Chiocca, Elena& Dati, Eleonora& Baroncelli, Giampiero I.& Cassio, Alessandra& Wasniewska, Malgorzata& Galluzzi, Fiorella…[et al.]. Central Precocious Puberty : Treatment with Triptorelin 11.25 mg. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-482701
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482701