Intravitreal Bevacizumab (Avastin) for Diabetic Retinopathy : The 2010 GLADAOF Lecture
Joint Authors
Alezzandrini, Arturo A.
Berrocal, Maria H.
Wu, Lihteh
Arevalo, J. Fernando
Morales-Cantón, Virgilio
Restrepo, Natalia
Farah, Michel Eid
Brito, Miguel
Lasave, Andres F.
Fromow-Guerra, Jans
Maia, Maurício
Sanchez, Juan G.
Bonafonte, Sergio
Saravia, Mario
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-30
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
This paper demonstrates multiple benefits of intravitreal bevacizumab (IVB) on diabetic retinopathy (DR) including diabetic macular edema (DME) and proliferative diabetic retinopathy (PDR) at 24 months of followup.
This is a retrospective multicenter interventional comparative case series of intravitreal injections of 1.25 or 2.5 mg of bevacizumab for DME, PDR without tractional retinal detachment (TRD), and patients who experienced the development or progression of TRD after an intravitreal injection of 1.25 or 2.5 mg of bevacizumab before vitrectomy for the management of PDR.
The results indicate that IVB injections may have a beneficial effect on macular thickness and visual acuity (VA) in diffuse DME.
Therefore, in the future this new therapy could complement focal/grid laser photocoagulation in DME.
In PDR, this new option could be an adjuvant agent to panretina photocoagulation so that more selective therapy may be applied.
Finally, TRD in PDR may occur or progress after IVB used as an adjuvant to vitrectomy.
Surgery should be performed 4 days after IVB.
Most patients had poorly controlled diabetes mellitus associated with elevated HbA1c, insulin administration, PDR refractory to panretinal photocoagulation, and longer time between IVB and vitrectomy.
American Psychological Association (APA)
Arevalo, J. Fernando& Sanchez, Juan G.& Lasave, Andres F.& Wu, Lihteh& Maia, Maurício& Bonafonte, Sergio…[et al.]. 2011. Intravitreal Bevacizumab (Avastin) for Diabetic Retinopathy : The 2010 GLADAOF Lecture. Journal of Ophthalmology،Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-482747
Modern Language Association (MLA)
Arevalo, J. Fernando…[et al.]. Intravitreal Bevacizumab (Avastin) for Diabetic Retinopathy : The 2010 GLADAOF Lecture. Journal of Ophthalmology No. 2011 (2011), pp.1-13.
https://search.emarefa.net/detail/BIM-482747
American Medical Association (AMA)
Arevalo, J. Fernando& Sanchez, Juan G.& Lasave, Andres F.& Wu, Lihteh& Maia, Maurício& Bonafonte, Sergio…[et al.]. Intravitreal Bevacizumab (Avastin) for Diabetic Retinopathy : The 2010 GLADAOF Lecture. Journal of Ophthalmology. 2011. Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-482747
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482747