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The Effect of Acid-Reducing Pharmacotherapy on the Severity of Nausea and Vomiting of Pregnancy
Joint Authors
Gill, Simerpal Kaur
Mastali, Katayoon
Koren, Gideon
Maltepe, Caroline
Source
Obstetrics and Gynecology International
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-07-01
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Heartburn and acid reflux (HB/RF) are associated with increased severity of nausea and vomiting.
The ability of acid-reducing drugs to reduce symptoms of nausea and vomiting of pregnancy has not been previously tested.
Objective.
To determine whether acid-reducing pharmacotherapy decreases the severity of NVP symptoms.
Methods.
We studied a cohort of women experiencing NVP, who were also experiencing HB/RF.
Women were counseled to commence acid-reducing pharmacotherapy.
The effectiveness of the acid-reducing medication in decreasing symptoms of both HB/RF and NVP was measured.
Results.
Acid-reducing drugs resulted in significant decreases in PUQE (9.6±3.0 to 6.5±2.5, P<.0001) and well-being scores from the initial (4.0±2.0) to the follow-up interview (6.8±1.6, P<.0001).
After intervention with acid-reducing pharmacotherapy, a reduction in acid symptoms correlated significantly with reduction in NVP (R2=0.72, P<.001).
Conclusion.
This is the first study to demonstrate that management of HB/RF can reduce the severity of NVP.
American Psychological Association (APA)
Gill, Simerpal Kaur& Maltepe, Caroline& Mastali, Katayoon& Koren, Gideon. 2009. The Effect of Acid-Reducing Pharmacotherapy on the Severity of Nausea and Vomiting of Pregnancy. Obstetrics and Gynecology International،Vol. 2009, no. 2009, pp.1-4.
https://search.emarefa.net/detail/BIM-482844
Modern Language Association (MLA)
Gill, Simerpal Kaur…[et al.]. The Effect of Acid-Reducing Pharmacotherapy on the Severity of Nausea and Vomiting of Pregnancy. Obstetrics and Gynecology International No. 2009 (2009), pp.1-4.
https://search.emarefa.net/detail/BIM-482844
American Medical Association (AMA)
Gill, Simerpal Kaur& Maltepe, Caroline& Mastali, Katayoon& Koren, Gideon. The Effect of Acid-Reducing Pharmacotherapy on the Severity of Nausea and Vomiting of Pregnancy. Obstetrics and Gynecology International. 2009. Vol. 2009, no. 2009, pp.1-4.
https://search.emarefa.net/detail/BIM-482844
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482844