Optimizing Surgical Margins in Breast Conservation
Joint Authors
Balci, Fatih Levent
Ananthakrishnan, Preya
Crowe, Joseph P.
Source
International Journal of Surgical Oncology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-09
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Adequate surgical margins in breast-conserving surgery for breast cancer have traditionally been viewed as a predictor of local recurrence rates.
There is still no consensus on what constitutes an adequate surgical margin, however it is clear that there is a trade-off between widely clear margins and acceptable cosmesis.
Preoperative approaches to plan extent of resection with appropriate margins (in the setting of surgery first as well as after neoadjuvant chemotherapy,) include mammography, US, and MRI.
Improvements have been made in preoperative lesion localization strategies for surgery, as well as intraoperative specimen assessment, in order to ensure complete removal of imaging findings and facilitate margin clearance.
Intraoperative strategies to accurately assess tumor and cavity margins include cavity shave techniques, as well as novel technologies for margin probes.
Ablative techniques, including radiofrequency ablation as well as intraoperative radiation, may be used to extend tumor-free margins without resecting additional tissue.
Oncoplastic techniques allow for wider resections while maintaining cosmesis and have acceptable local recurrence rates, however often involve surgery on the contralateral breast.
As systemic therapy for breast cancer continues to improve, it is unclear what the importance of surgical margins on local control rates will be in the future.
American Psychological Association (APA)
Ananthakrishnan, Preya& Balci, Fatih Levent& Crowe, Joseph P.. 2012. Optimizing Surgical Margins in Breast Conservation. International Journal of Surgical Oncology،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-482867
Modern Language Association (MLA)
Ananthakrishnan, Preya…[et al.]. Optimizing Surgical Margins in Breast Conservation. International Journal of Surgical Oncology No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-482867
American Medical Association (AMA)
Ananthakrishnan, Preya& Balci, Fatih Levent& Crowe, Joseph P.. Optimizing Surgical Margins in Breast Conservation. International Journal of Surgical Oncology. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-482867
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482867