The Interaction between Diabetes, Body Mass Index, Hepatic Steatosis, and Risk of Liver Resection : Insulin Dependent Diabetes Is the Greatest Risk for Major Complications
Joint Authors
Stell, D. A.
Shahtahmassebi, G.
Bowles, M. J.
Aroori, S.
Wiggans, M. G.
Lordan, Jeffrey T.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-14
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
This study aimed to assess the relationship between diabetes, obesity, and hepatic steatosis in patients undergoing liver resection and to determine if these factors are independent predictors of major complications.
Materials and Methods.
Analysis of a prospectively maintained database of patients undergoing liver resection between 2005 and 2012 was undertaken.
Background liver was assessed for steatosis and classified as <33% and ≥33%.
Major complications were defined as Grade III–V complications using the Dindo-Clavien classification.
Results.
504 patients underwent liver resection, of whom 56 had diabetes and 61 had steatosis ≥33%.
Median BMI was 26 kg/m2 (16–54 kg/m2).
94 patients developed a major complication (18.7%).
BMI ≥ 25 kg/m2 (P=0.001) and diabetes (P=0.018) were associated with steatosis ≥33%.
Only insulin dependent diabetes was a risk factor for major complications (P=0.028).
Age, male gender, hypoalbuminaemia, synchronous bowel procedures, extent of resection, and blood transfusion were also independent risk factors.
Conclusions.
Liver surgery in the presence of steatosis, elevated BMI, and non-insulin dependent diabetes is not associated with major complications.
Although diabetes requiring insulin therapy was a significant risk factor, the major risk factors relate to technical aspects of surgery, particularly synchronous bowel procedures.
American Psychological Association (APA)
Wiggans, M. G.& Lordan, Jeffrey T.& Shahtahmassebi, G.& Aroori, S.& Bowles, M. J.& Stell, D. A.. 2014. The Interaction between Diabetes, Body Mass Index, Hepatic Steatosis, and Risk of Liver Resection : Insulin Dependent Diabetes Is the Greatest Risk for Major Complications. HPB Surgery،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-482910
Modern Language Association (MLA)
Wiggans, M. G.…[et al.]. The Interaction between Diabetes, Body Mass Index, Hepatic Steatosis, and Risk of Liver Resection : Insulin Dependent Diabetes Is the Greatest Risk for Major Complications. HPB Surgery No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-482910
American Medical Association (AMA)
Wiggans, M. G.& Lordan, Jeffrey T.& Shahtahmassebi, G.& Aroori, S.& Bowles, M. J.& Stell, D. A.. The Interaction between Diabetes, Body Mass Index, Hepatic Steatosis, and Risk of Liver Resection : Insulin Dependent Diabetes Is the Greatest Risk for Major Complications. HPB Surgery. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-482910
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482910