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Identification of Pentatricopeptide Repeat Proteins in the Model Organism Dictyostelium discoideum
Joint Authors
Barth, Christian
Brewster, Jessica
Manna, Sam
Source
International Journal of Genomics
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-12
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Pentatricopeptide repeat (PPR) proteins are RNA binding proteins with functions in organelle RNA metabolism.
They are found in all eukaryotes but have been most extensively studied in plants.
We report on the identification of 12 PPR-encoding genes in the genome of the protist Dictyostelium discoideum, with potential homologs in other members of the same lineage and some predicted novel functions for the encoded gene products in protists.
For one of the gene products, we show that it localizes to the mitochondria, and we also demonstrate that antisense inhibition of its expression leads to slower growth, a phenotype associated with mitochondrial dysfunction.
American Psychological Association (APA)
Manna, Sam& Brewster, Jessica& Barth, Christian. 2013. Identification of Pentatricopeptide Repeat Proteins in the Model Organism Dictyostelium discoideum. International Journal of Genomics،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-482953
Modern Language Association (MLA)
Manna, Sam…[et al.]. Identification of Pentatricopeptide Repeat Proteins in the Model Organism Dictyostelium discoideum. International Journal of Genomics No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-482953
American Medical Association (AMA)
Manna, Sam& Brewster, Jessica& Barth, Christian. Identification of Pentatricopeptide Repeat Proteins in the Model Organism Dictyostelium discoideum. International Journal of Genomics. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-482953
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482953