The Severity of Fatty Liver Disease Relating to Metabolic Abnormalities Independently Predicts Coronary Calcification
Joint Authors
Lee, Ying-Hsiang
Liu, Chuan-Chuan
Hou, Charles Jia-Yin
Hung, Chung-Lieh
Shih, Shou-Chuan
Tsai, Cheng-Ho
Yeh, Hung-I.
Wu, Yih-Jer
Source
Radiology Research and Practice
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-27
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Nonalcoholic fatty liver disease (NAFLD) is one of the metabolic disorders presented in liver.
The relationship between severity of NAFLD and coronary atherosclerotic burden remains largely unknown.
Methods and Materials.
We analyzed subjects undergoing coronary calcium score evaluation by computed tomography (MDCT) and fatty liver assessment using abdominal ultrasonography.
Framingham risk score (FRS) and metabolic risk score (MRS) were obtained in all subjects.
A graded, semiquantitative score was established to quantify the severity of NAFLD.
Multivariate logistic regression analysis was used to depict the association between NAFLD and calcium score.
Results.
Of all, 342 participants (female: 22.5%, mean age: 48.7±7.0 years) met the sufficient information rendering detailed analysis.
The severity of NAFLD was positively associated with MRS (X2=6.12, trend P<0.001) and FRS (X2=5.88, trend P<0.001).
After multivariable adjustment for clinical variables and life styles, the existence of moderate to severe NAFLD was independently associated with abnormal calcium score (P<0.05).
Conclusion.
The severity of NAFLD correlated well with metabolic abnormality and was independently predict coronary calcification beyond clinical factors.
Our data suggests that NAFLD based on ultrasonogram could positively reflect the burden of coronary calcification.
American Psychological Association (APA)
Lee, Ying-Hsiang& Wu, Yih-Jer& Liu, Chuan-Chuan& Hou, Charles Jia-Yin& Yeh, Hung-I.& Tsai, Cheng-Ho…[et al.]. 2011. The Severity of Fatty Liver Disease Relating to Metabolic Abnormalities Independently Predicts Coronary Calcification. Radiology Research and Practice،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-482974
Modern Language Association (MLA)
Lee, Ying-Hsiang…[et al.]. The Severity of Fatty Liver Disease Relating to Metabolic Abnormalities Independently Predicts Coronary Calcification. Radiology Research and Practice No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-482974
American Medical Association (AMA)
Lee, Ying-Hsiang& Wu, Yih-Jer& Liu, Chuan-Chuan& Hou, Charles Jia-Yin& Yeh, Hung-I.& Tsai, Cheng-Ho…[et al.]. The Severity of Fatty Liver Disease Relating to Metabolic Abnormalities Independently Predicts Coronary Calcification. Radiology Research and Practice. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-482974
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482974