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Time-Intensity Curve Parameters in Rectal Cancer Measured Using Endorectal Ultrasonography with Sterile Coupling Gels Filling the Rectum : Correlations with Tumor Angiogenesis and Clinicopathological Features
Joint Authors
Li, Lin
Zou, Shuang-Mei
Cui, Ning-Yi
Wang, Yi-Xiang J.
Wang, Yong
Jiang, Yu-Xin
Zhou, Chun-Wu
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-12
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The primary aim of this study was to investigate the relationship between contrast-enhanced ultrasonography (CEUS) imaging parameters and clinicopathological features of rectal carcinoma and assess their potential as new radiological prognostic predictors.
A total of 66 rectal carcinoma patients were analyzed with the time-intensity curve of CEUS.
The parameter arrival time (AT), time to peak enhancement (TTP), wash-in time (WIT), enhanced intensity (EI), and ascending slope (AS) were measured.
Microvessel density (MVD) was evaluated by immunohistochemical staining of surgical specimens.
All findings were analysed prospectively and correlated with tumor staging, histological grading, and MVD.
The mean values of AT, TTP, WIT, EI, and AS value of the rectal carcinoma were 10.84±3.28 s,20.61±5.52 s,9.78±2.83 s,28.68±4.67 dB, and 3.20±1.10, respectively.
A positive linear correlation was found between the EI and MVD in rectal carcinoma (r=0.295,P=0.016), and there was a significant difference for EI among histological grading (r=-0.264,P=0.007).
EI decreased as T stage increased with a trend of association noted (P=0.096).
EI of contrast enhanced endorectal ultrasonography provides noninvasive biomarker of tumor angiogenesis in rectal cancer.
CEUS data have the potential to predict patient prognosis.
American Psychological Association (APA)
Wang, Yong& Li, Lin& Wang, Yi-Xiang J.& Cui, Ning-Yi& Zou, Shuang-Mei& Zhou, Chun-Wu…[et al.]. 2014. Time-Intensity Curve Parameters in Rectal Cancer Measured Using Endorectal Ultrasonography with Sterile Coupling Gels Filling the Rectum : Correlations with Tumor Angiogenesis and Clinicopathological Features. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-483075
Modern Language Association (MLA)
Wang, Yong…[et al.]. Time-Intensity Curve Parameters in Rectal Cancer Measured Using Endorectal Ultrasonography with Sterile Coupling Gels Filling the Rectum : Correlations with Tumor Angiogenesis and Clinicopathological Features. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-483075
American Medical Association (AMA)
Wang, Yong& Li, Lin& Wang, Yi-Xiang J.& Cui, Ning-Yi& Zou, Shuang-Mei& Zhou, Chun-Wu…[et al.]. Time-Intensity Curve Parameters in Rectal Cancer Measured Using Endorectal Ultrasonography with Sterile Coupling Gels Filling the Rectum : Correlations with Tumor Angiogenesis and Clinicopathological Features. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-483075
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483075