The Biological Side of Water-Soluble Arene Ruthenium Assemblies
Joint Authors
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-20, 20 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-17
Country of Publication
Egypt
No. of Pages
20
Main Subjects
Abstract EN
This review article covers the synthetic strategies, structural aspects, and host-guest properties of ruthenium metalla-assemblies, with a special focus on their use as drug delivery vectors.
The two-dimensional metalla-rectangles show interesting host-guest possibilities but seem less appropriate for being used as drug carriers.
On the other hand, metalla-prisms allow encapsulation and possible targeted release of bioactive molecules and consequently show some potential as drug delivery vectors.
The reactivity of these metalla-prisms can be fine-tuned to allow a fine control of the guest’s release.
The larger metalla-cubes can be used to stabilize the formation of G-quadruplex DNA and can be used to encapsulate and release photoactive molecules such as porphins.
These metalla-assemblies demonstrate great prospective in photodynamic therapy.
American Psychological Association (APA)
Therrien, Bruno& Furrer, Julien. 2014. The Biological Side of Water-Soluble Arene Ruthenium Assemblies. Advances in Chemistry،Vol. 2014, no. 2014, pp.1-20.
https://search.emarefa.net/detail/BIM-483177
Modern Language Association (MLA)
Therrien, Bruno& Furrer, Julien. The Biological Side of Water-Soluble Arene Ruthenium Assemblies. Advances in Chemistry No. 2014 (2014), pp.1-20.
https://search.emarefa.net/detail/BIM-483177
American Medical Association (AMA)
Therrien, Bruno& Furrer, Julien. The Biological Side of Water-Soluble Arene Ruthenium Assemblies. Advances in Chemistry. 2014. Vol. 2014, no. 2014, pp.1-20.
https://search.emarefa.net/detail/BIM-483177
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483177