Short Interval Infield Sarcoma Development following Resection of Glioblastoma and Adjuvant Radiotherapy and Temozolomide

Abstract EN

Background.

The development of 2 unassociated brain cancers in the same patient is a rare occurrence.

Secondary cancers are generally thought to develop as an oncogenic consequence of the radiation therapy delivered to treat the primary cancers, always requiring a significant time interval between radiation treatment and secondary cancer development.

Case Description.

We report the development of an undifferentiated myxoid sarcoma only 13 months following radiation therapy for a glioblastoma.

Conclusion.

This case represents the shortest time interval reported between radiation therapy and secondary brain cancer development.