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Hox Transcription Factors : Modulators of Cell-Cell and Cell-Extracellular Matrix Adhesion
Author
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-20
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Hox genes encode homeodomain-containing transcription factors that determine cell and tissue identities in the embryo during development.
Hox genes are also expressed in various adult tissues and cancer cells.
In Drosophila, expression of cell adhesion molecules, cadherins and integrins, is regulated by Hox proteins operating in hierarchical molecular pathways and plays a crucial role in segment-specific organogenesis.
A number of studies using mammalian cultured cells have revealed that cell adhesion molecules responsible for cell-cell and cell-extracellular matrix interactions are downstream targets of Hox proteins.
However, whether Hox transcription factors regulate expression of cell adhesion molecules during vertebrate development is still not fully understood.
In this review, the potential roles Hox proteins play in cell adhesion and migration during vertebrate body patterning are discussed.
American Psychological Association (APA)
Taniguchi, Yasushi. 2014. Hox Transcription Factors : Modulators of Cell-Cell and Cell-Extracellular Matrix Adhesion. BioMed Research International،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-483328
Modern Language Association (MLA)
Taniguchi, Yasushi. Hox Transcription Factors : Modulators of Cell-Cell and Cell-Extracellular Matrix Adhesion. BioMed Research International No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-483328
American Medical Association (AMA)
Taniguchi, Yasushi. Hox Transcription Factors : Modulators of Cell-Cell and Cell-Extracellular Matrix Adhesion. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-483328
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483328