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Cooperation of Cancer Stem Cell Properties and Epithelial-Mesenchymal Transition in the Establishment of Breast Cancer Metastasis
Joint Authors
Hayashida, Tetsu
Kitagawa, Yuko
Jinno, Hiromitsu
Kitajima, Masaki
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-12-23
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Epithelial-mesenchymal transition (EMT) is a multistep process in which cells acquire molecular alterations such as loss of cell-cell junctions and restructuring of the cytoskeleton.
There is an increasing understanding that this process may promote breast cancer progression through promotion of invasive and metastatic tumor growth.
Recent observations imply that there may be a cross-talk between EMT and cancer stem cell properties, leading to enhanced tumorigenicity and the capacity to generate heterogeneous tumor cell populations.
Here, we review the experimental and clinical evidence for the involvement of EMT in cancer stem cell theory, focusing on the common characteristics of this phenomenon.
American Psychological Association (APA)
Hayashida, Tetsu& Jinno, Hiromitsu& Kitagawa, Yuko& Kitajima, Masaki. 2010. Cooperation of Cancer Stem Cell Properties and Epithelial-Mesenchymal Transition in the Establishment of Breast Cancer Metastasis. Journal of Oncology،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-483331
Modern Language Association (MLA)
Hayashida, Tetsu…[et al.]. Cooperation of Cancer Stem Cell Properties and Epithelial-Mesenchymal Transition in the Establishment of Breast Cancer Metastasis. Journal of Oncology No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-483331
American Medical Association (AMA)
Hayashida, Tetsu& Jinno, Hiromitsu& Kitagawa, Yuko& Kitajima, Masaki. Cooperation of Cancer Stem Cell Properties and Epithelial-Mesenchymal Transition in the Establishment of Breast Cancer Metastasis. Journal of Oncology. 2010. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-483331
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483331