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The Anti-Inflammatory Effects of Acupuncture and Their Relevance to Allergic Rhinitis : A Narrative Review and Proposed Model
Joint Authors
Cripps, Allan W.
Smith, Peter K.
McDonald, John L.
Golianu, Brenda
Xue, Charlie Changli
Smith, Caroline A.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-14
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Classical literature indicates that acupuncture has been used for millennia to treat numerous inflammatory conditions, including allergic rhinitis.
Recent research has examined some of the mechanisms underpinning acupuncture's anti-inflammatory effects which include mediation by sympathetic and parasympathetic pathways.
The hypothalamus-pituitary-adrenal (HPA) axis has been reported to mediate the antioedema effects of acupuncture, but not antihyperalgesic actions during inflammation.
Other reported anti-inflammatory effects of acupuncture include an antihistamine action and downregulation of proinflammatory cytokines (such as TNF-α, IL-1β, IL-6, and IL-10), proinflammatory neuropeptides (such as SP, CGRP, and VIP), and neurotrophins (such as NGF and BDNF) which can enhance and prolong inflammatory response.
Acupuncture has been reported to suppress the expression of COX-1, COX-2, and iNOS during experimentally induced inflammation.
Downregulation of the expression and sensitivity of the transient receptor potential vallinoid 1 (TRPV1) after acupuncture has been reported.
In summary, acupuncture may exert anti-inflammatory effects through a complex neuro-endocrino-immunological network of actions.
Many of these generic anti-inflammatory effects of acupuncture are of direct relevance to allergic rhinitis; however, more research is needed to elucidate specifically how immune mechanisms might be modulated by acupuncture in allergic rhinitis, and to this end a proposed model is offered to guide further research.
American Psychological Association (APA)
McDonald, John L.& Cripps, Allan W.& Smith, Peter K.& Smith, Caroline A.& Xue, Charlie Changli& Golianu, Brenda. 2013. The Anti-Inflammatory Effects of Acupuncture and Their Relevance to Allergic Rhinitis : A Narrative Review and Proposed Model. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-483368
Modern Language Association (MLA)
McDonald, John L.…[et al.]. The Anti-Inflammatory Effects of Acupuncture and Their Relevance to Allergic Rhinitis : A Narrative Review and Proposed Model. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-483368
American Medical Association (AMA)
McDonald, John L.& Cripps, Allan W.& Smith, Peter K.& Smith, Caroline A.& Xue, Charlie Changli& Golianu, Brenda. The Anti-Inflammatory Effects of Acupuncture and Their Relevance to Allergic Rhinitis : A Narrative Review and Proposed Model. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-483368
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483368