When Ribonucleases Come into Play in Pathogens : A Survey of Gram-Positive Bacteria
Joint Authors
Lioliou, Efthimia
Jester, Brian C.
Romby, Pascale
Source
International Journal of Microbiology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-13
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Abstract EN
It is widely acknowledged that RNA stability plays critical roles in bacterial adaptation and survival in different environments like those encountered when bacteria infect a host.
Bacterial ribonucleases acting alone or in concert with regulatory RNAs or RNA binding proteins are the mediators of the regulatory outcome on RNA stability.
We will give a current update of what is known about ribonucleases in the model Gram-positive organism Bacillus subtilis and will describe their established roles in virulence in several Gram-positive pathogenic bacteria that are imposing major health concerns worldwide.
Implications on bacterial evolution through stabilization/transfer of genetic material (phage or plasmid DNA) as a result of ribonucleases' functions will be covered.
The role of ribonucleases in emergence of antibiotic resistance and new concepts in drug design will additionally be discussed.
American Psychological Association (APA)
Jester, Brian C.& Romby, Pascale& Lioliou, Efthimia. 2012. When Ribonucleases Come into Play in Pathogens : A Survey of Gram-Positive Bacteria. International Journal of Microbiology،Vol. 2012, no. 2012, pp.1-18.
https://search.emarefa.net/detail/BIM-483404
Modern Language Association (MLA)
Jester, Brian C.…[et al.]. When Ribonucleases Come into Play in Pathogens : A Survey of Gram-Positive Bacteria. International Journal of Microbiology No. 2012 (2012), pp.1-18.
https://search.emarefa.net/detail/BIM-483404
American Medical Association (AMA)
Jester, Brian C.& Romby, Pascale& Lioliou, Efthimia. When Ribonucleases Come into Play in Pathogens : A Survey of Gram-Positive Bacteria. International Journal of Microbiology. 2012. Vol. 2012, no. 2012, pp.1-18.
https://search.emarefa.net/detail/BIM-483404
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483404