Influence of a Medium-Impact Exercise Program on Health-Related Quality of Life and Cardiorespiratory Fitness in Females with Subclinical Hypothyroidism : An Open-Label Pilot Study

Abstract EN

Objective.

To examine the influence of a medium-impact exercise program (MIEP) on health-related quality of life (HRQoL) and cardiorespiratory fitness (VO2max) in females with subclinical hypothyroidism (sHT).

Materials and Methods.

We selected 17 sedentary women with sHT (mean age: 43.1 (standard deviation: 9.7) years).

Participants carried out an MIEP consisting of 3 weekly sessions of 60 minutes during 12 weeks.

Before and after the exercise program HRQoL was assessed by the SF-12v2 questionnaire, and VO2max was evaluated by Rockport walk test.

Results.

After the 12-week intervention, the participants that performed an MIEP showed improvements in HRQoL in most domains, particularly the vitality domain by 7 points, the social functioning domain by 10 points, the mental health domain by 7 points, and the mental component summary by 7 points.

One of the four domains within the physical component summary (general health domain) showed significant effect of the exercise intervention: 6 points.

Moreover, the participants that performed exercise showed a higher VO2max (28%; P<0.01).

Conclusion.

After 12 weeks of medium-impact exercise program, there were remarkable improvements in HRQoL in most domains.

Moreover, this exercise program proved to have a positive influence on cardiorespiratory fitness.