MicroRNAs in Soft Tissue Sarcomas : Overview of the Accumulating Evidence and Importance as Novel Biomarkers
Joint Authors
Takeda, Ken
Ozaki, Toshifumi
Kunisada, Toshiyuki
Uotani, Koji
Ochiya, Takahiro
Fujiwara, Tomohiro
Yoshida, Aki
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-04
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Sarcomas are distinctly heterogeneous tumors and a variety of subtypes have been described.
Although several diagnostic explorations in the past three decades, such as identification of chromosomal translocation, have greatly improved the diagnosis of soft tissue sarcomas, the unsolved issues, including the limited useful biomarkers, remain.
Emerging reports on miRNAs in soft tissue sarcomas have provided clues to solving these problems.
Evidence of circulating miRNAs in patients with soft tissue sarcomas and healthy individuals has been accumulated and is accelerating their potential to develop into clinical applications.
Moreover, miRNAs that function as novel prognostic factors have been identified, thereby facilitating their use in miRNA-targeted therapy.
In this review, we provide an overview of the current knowledge on miRNA deregulation in soft tissue sarcomas, and discuss their potential as novel biomarkers and therapeutics.
American Psychological Association (APA)
Fujiwara, Tomohiro& Kunisada, Toshiyuki& Takeda, Ken& Uotani, Koji& Yoshida, Aki& Ochiya, Takahiro…[et al.]. 2014. MicroRNAs in Soft Tissue Sarcomas : Overview of the Accumulating Evidence and Importance as Novel Biomarkers. BioMed Research International،Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-483473
Modern Language Association (MLA)
Fujiwara, Tomohiro…[et al.]. MicroRNAs in Soft Tissue Sarcomas : Overview of the Accumulating Evidence and Importance as Novel Biomarkers. BioMed Research International No. 2014 (2014), pp.1-15.
https://search.emarefa.net/detail/BIM-483473
American Medical Association (AMA)
Fujiwara, Tomohiro& Kunisada, Toshiyuki& Takeda, Ken& Uotani, Koji& Yoshida, Aki& Ochiya, Takahiro…[et al.]. MicroRNAs in Soft Tissue Sarcomas : Overview of the Accumulating Evidence and Importance as Novel Biomarkers. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-483473
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483473