Epigenetics and Autoimmune Diseases
Joint Authors
Montoya-Ortiz, Gladys
Quintero-Ronderos, Paula
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-22
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Epigenetics is defined as the study of all inheritable and potentially reversible changes in genome function that do not alter the nucleotide sequence within the DNA.
Epigenetic mechanisms such as DNA methylation, histone modification, nucleosome positioning, and microRNAs (miRNAs) are essential to carry out key functions in the regulation of gene expression.
Therefore, the epigenetic mechanisms are a window to understanding the possible mechanisms involved in the pathogenesis of complex diseases such as autoimmune diseases.
It is noteworthy that autoimmune diseases do not have the same epidemiology, pathology, or symptoms but do have a common origin that can be explained by the sharing of immunogenetic mechanisms.
Currently, epigenetic research is looking for disruption in one or more epigenetic mechanisms to provide new insights into autoimmune diseases.
The identification of cell-specific targets of epigenetic deregulation will serve us as clinical markers for diagnosis, disease progression, and therapy approaches.
American Psychological Association (APA)
Quintero-Ronderos, Paula& Montoya-Ortiz, Gladys. 2012. Epigenetics and Autoimmune Diseases. Autoimmune Diseases،Vol. 2012, no. 2012, pp.1-16.
https://search.emarefa.net/detail/BIM-483565
Modern Language Association (MLA)
Quintero-Ronderos, Paula& Montoya-Ortiz, Gladys. Epigenetics and Autoimmune Diseases. Autoimmune Diseases No. 2012 (2012), pp.1-16.
https://search.emarefa.net/detail/BIM-483565
American Medical Association (AMA)
Quintero-Ronderos, Paula& Montoya-Ortiz, Gladys. Epigenetics and Autoimmune Diseases. Autoimmune Diseases. 2012. Vol. 2012, no. 2012, pp.1-16.
https://search.emarefa.net/detail/BIM-483565
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483565