Nasopharyngeal Carcinoma Signaling Pathway : An Update on Molecular Biomarkers
Joint Authors
Tulalamba, Warut
Janvilisri, Tavan
Source
International Journal of Cell Biology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-05
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Nasopharyngeal carcinoma (NPC) is an uncommon cancer, which has a distinctive ethnic and geographic distribution.
Etiology of NPC is considered to be related with a complex interaction of environmental and genetic factors as well as Epstein-Barr virus infection.
Since NPC is located in the silent painless area, the disease is usually therefore diagnosed at the advanced stages; hence early detection of NPC is difficult.
Furthermore, understanding in molecular pathogenesis is still lacking, pondering the identification of effective prognostic and diagnostic biomarkers.
Dysregulation of signaling molecules in intracellular signal transduction, which regulate cell proliferation, apoptosis, and adhesion, underlines the basis of NPC pathogenesis.
In this paper, the molecular signaling pathways in the NPC are discussed for the holistic view of NPC development and progression.
The important insights toward NPC pathogenesis may offer strategies for identification of novel biomarkers for diagnosis and prognosis.
American Psychological Association (APA)
Tulalamba, Warut& Janvilisri, Tavan. 2012. Nasopharyngeal Carcinoma Signaling Pathway : An Update on Molecular Biomarkers. International Journal of Cell Biology،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-483646
Modern Language Association (MLA)
Tulalamba, Warut& Janvilisri, Tavan. Nasopharyngeal Carcinoma Signaling Pathway : An Update on Molecular Biomarkers. International Journal of Cell Biology No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-483646
American Medical Association (AMA)
Tulalamba, Warut& Janvilisri, Tavan. Nasopharyngeal Carcinoma Signaling Pathway : An Update on Molecular Biomarkers. International Journal of Cell Biology. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-483646
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483646