Potential Infectious Etiology of Behçet's Disease
Joint Authors
Colucci, Roberta
Moretti, Silvia
Lotti, Torello
Galeone, Massimiliano
D'Erme, Angelo Massimiliano
Source
Pathology Research International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-29
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Behçet's disease is a multisystem inflammatory disorder characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and skin lesions.
The cause of Behçet's disease remains unknown, but epidemiologic findings suggest that an autoimmune process is triggered by an environmental agent in a genetically predisposed individual.
An infectious agent could operate through molecular mimicry, and subsequently the disease could be perpetuated by an abnormal immune response to an autoantigen in the absence of ongoing infection.
Potentia bacterial are Saccharomyces cerevisiae, mycobacteria, Borrelia burgdorferi, Helicobacter pylori, Escherichia coli, Staphylococcus aureus, and Mycoplasma fermentans, but the most commonly investigated microorganism is Streptococcus sanguinis.
The relationship between streptococcal infections and Behçet's disease is suggested by clinical observations that an unhygienic oral condition is frequently noted in the oral cavity of Behçet's disease patients.
Several viral agents, including herpes simplex virus-1, hepatitis C virus, parvovirus B19, cytomegalovirus, Epstein-Barr virus and varicella zoster virus, may also have some role.
American Psychological Association (APA)
Galeone, Massimiliano& Colucci, Roberta& D'Erme, Angelo Massimiliano& Moretti, Silvia& Lotti, Torello. 2011. Potential Infectious Etiology of Behçet's Disease. Pathology Research International،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-483713
Modern Language Association (MLA)
Galeone, Massimiliano…[et al.]. Potential Infectious Etiology of Behçet's Disease. Pathology Research International No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-483713
American Medical Association (AMA)
Galeone, Massimiliano& Colucci, Roberta& D'Erme, Angelo Massimiliano& Moretti, Silvia& Lotti, Torello. Potential Infectious Etiology of Behçet's Disease. Pathology Research International. 2011. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-483713
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483713