Laser Ablation for Small Hepatocellular Carcinoma
Joint Authors
Di Costanzo, Giovanni Giuseppe
Francica, Giampiero
Pacella, Claudio Maurizio
Source
Radiology Research and Practice
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-04
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide and is increasingly detected at small size (<5 cm) owing to surveillance programmes in high-risk patients.
For these cases, curative therapies such as resection, liver transplantation, or percutaneous ablation have been proposed.
When surgical options are precluded, image-guided tumor ablation is recommended as the most appropriate therapeutic choice in terms of tumor local control, safety, and improvement in survival.
Laser ablation (LA) represents one of currently available loco-ablative techniques: light is delivered via flexible quartz fibers of diameter from 300 to 600 μm inserted into tumor lesion through either fine needles (21g Chiba needles) or large-bore catheters.
The thermal destruction of tissue is achieved through conversion of absorbed light (usually infrared) into heat.
A range of different imaging modalities have been used to guide percutaneous laser ablation, but ultrasound and magnetic resonance imaging are most widely employed, according to local experience and resource availability.
Available clinical data suggest that LA is highly effective in terms of tumoricidal capability with an excellent safety profile; the best results in terms of long-term survival are obtained in early HCC so that LA can be proposed not only in unresectable cases but, not differently from radiofrequency ablation, also as the first-line treatment.
American Psychological Association (APA)
Pacella, Claudio Maurizio& Francica, Giampiero& Di Costanzo, Giovanni Giuseppe. 2011. Laser Ablation for Small Hepatocellular Carcinoma. Radiology Research and Practice،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-483730
Modern Language Association (MLA)
Pacella, Claudio Maurizio…[et al.]. Laser Ablation for Small Hepatocellular Carcinoma. Radiology Research and Practice No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-483730
American Medical Association (AMA)
Pacella, Claudio Maurizio& Francica, Giampiero& Di Costanzo, Giovanni Giuseppe. Laser Ablation for Small Hepatocellular Carcinoma. Radiology Research and Practice. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-483730
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483730