Thyroid and Hepatic Haemodynamic Alterations among Egyptian Children with Liver Cirrhosis
Joint Authors
El-Kabbany, Zeinab A.
Tawfik, Lamis M.
Abd El Hakim, Ahmed S.
Hamza, Rasha T.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-30
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Alterations in thyroid hormones regulation and metabolism are frequently observed in patients with cirrhosis.
Aims.
To assess alterations in thyroid volume (TV), haemodynamics, and hormones in patients with cirrhosis and their relation to hepatic arterial haemodynamics, and disease severity.
Methods.
Forty cirrhotic patients were compared to 30 healthy subjects regarding TV, free triiodiothyronine (fT3), free tetraiodothyronine (fT4), thyroid stimulating hormone (TSH), and pulsatility and resistance indices in the inferior thyroid and hepatic arteries.
Results.
TV (P=0.042), thyroid volume standard deviation score (TVSDS, P=0.001), Inferior Thyroid Artery Pulsatility Index (ITAPI, P=0.001), Inferior Thyroid Artery Resistance Index (ITARI, P=0.041), Hepatic Artery Pulsatility Index (HAPI, P=0.029) and Hepatic Artery Resistance Index (HARI, P=0.035) were higher among cases being highest in Child-C patients.
FT3 was lower in patients than controls (P=0.001) and correlated negatively with ITAPI (r=−0.71, P=0.021) and ITARI (r=−0.79, P=0.011).
ITAPI and ITARI correlated directly with HAPI and HARI (r=0.62, P=0.03, and r=0.42, P=0.04, resp.).
Conclusions.
Thyroid is involved in the haemodynamic alterations of cirrhosis.
Routine study of thyroid by Doppler and assessment of thyroid functions should be performed in patients with cirrhosis to offer proper treatment if needed.
American Psychological Association (APA)
El-Kabbany, Zeinab A.& Hamza, Rasha T.& Abd El Hakim, Ahmed S.& Tawfik, Lamis M.. 2012. Thyroid and Hepatic Haemodynamic Alterations among Egyptian Children with Liver Cirrhosis. ISRN Gastroenterology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-483735
Modern Language Association (MLA)
El-Kabbany, Zeinab A.…[et al.]. Thyroid and Hepatic Haemodynamic Alterations among Egyptian Children with Liver Cirrhosis. ISRN Gastroenterology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-483735
American Medical Association (AMA)
El-Kabbany, Zeinab A.& Hamza, Rasha T.& Abd El Hakim, Ahmed S.& Tawfik, Lamis M.. Thyroid and Hepatic Haemodynamic Alterations among Egyptian Children with Liver Cirrhosis. ISRN Gastroenterology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-483735
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483735