Primary Corneal Squamous Cell Carcinoma in a Dog : Clinical and Histopathological Evaluation
Joint Authors
Marchetti, Veronica
Ressel, Lorenzo
Barsotti, Giovanni
Millanta, Francesca
Finotello, Riccardo
Source
Case Reports in Veterinary Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
An 8-year-old male pug with a 12-month history of a progressive nonpainful mass on the left cornea was evaluated.
Ocular examination showed a severe bilateral keratoconjunctivitis sicca, pigmentary keratitis, and an exophytic irregular pink mass occupying approximately 75% of the total corneal surface of the left eye.
A squamous cell carcinoma (SCC) was suspected on cytology, and clinical investigations showed no evidence of metastases.
A transpalpebral enucleation was therefore performed, and the diagnosis of SCC was confirmed on histopathology.
Immunohistochemical investigations showed that the neoplastic cells were pan-cytokeratin positive and vimentin negative.
Additionally, nuclei immunoreactive to Ki-67 antigen were detected.
Tumor cells were also negative to p53.
Immunoreactivity to COX-2 was found in less than 10% of the neoplastic cells.
No adjuvant therapies were instituted, and no evidence of local recurrence or distance metastasis was identified during the 24-month follow-up period.
American Psychological Association (APA)
Barsotti, Giovanni& Ressel, Lorenzo& Finotello, Riccardo& Marchetti, Veronica& Millanta, Francesca. 2012. Primary Corneal Squamous Cell Carcinoma in a Dog : Clinical and Histopathological Evaluation. Case Reports in Veterinary Medicine،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-483824
Modern Language Association (MLA)
Barsotti, Giovanni…[et al.]. Primary Corneal Squamous Cell Carcinoma in a Dog : Clinical and Histopathological Evaluation. Case Reports in Veterinary Medicine No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-483824
American Medical Association (AMA)
Barsotti, Giovanni& Ressel, Lorenzo& Finotello, Riccardo& Marchetti, Veronica& Millanta, Francesca. Primary Corneal Squamous Cell Carcinoma in a Dog : Clinical and Histopathological Evaluation. Case Reports in Veterinary Medicine. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-483824
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483824