Diagnostic Potential of Distortion Product Otoacoustic Emissions in Noninvasive Assessment of Elevated Intracranial Pressure : Different Patterns of DPOAE Alterations in the Guinea Pig
Joint Authors
Mees, Klaus
Canis, Martin
Strassen, Ulrich
Plesnila, Nikolaus
Strieth, Sebastian
Deppe, Christoph
Olzowy, Bernhard
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-28
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Distortion product otoacoustic emissions (DPOAEs) have been proposed for monitoring the intracranial pressure (ICP) noninvasively.
Aim of this study was to establish an animal model in the guinea pig for a detailed characterisation of ICP-related DPOAE alterations.
In guinea pigs, the ICP was elevated experimentally and the DPOAE levels were continuously monitored.
Two different patterns of DPOAE level changes were observed: (1) a decrease of few decibels affecting mainly the frequency f2 = 2 kHz with instant recovery after normalization of ICP, probably related to alterations of middle ear sound transmission; (2) a more pronounced level decrease affecting all frequencies, combined with a second decrease and prolonged recovery after ICP normalization, which might be related to alterations of the cochlear blood flow.
Alterations of the levels of DPOAEs might not only provide information about ICP but also indicate critical ICP-induced reductions of the cochlear and the cerebral perfusion pressure.
American Psychological Association (APA)
Strassen, Ulrich& Deppe, Christoph& Mees, Klaus& Plesnila, Nikolaus& Canis, Martin& Strieth, Sebastian…[et al.]. 2011. Diagnostic Potential of Distortion Product Otoacoustic Emissions in Noninvasive Assessment of Elevated Intracranial Pressure : Different Patterns of DPOAE Alterations in the Guinea Pig. ISRN Anesthesiology،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-483843
Modern Language Association (MLA)
Strassen, Ulrich…[et al.]. Diagnostic Potential of Distortion Product Otoacoustic Emissions in Noninvasive Assessment of Elevated Intracranial Pressure : Different Patterns of DPOAE Alterations in the Guinea Pig. ISRN Anesthesiology No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-483843
American Medical Association (AMA)
Strassen, Ulrich& Deppe, Christoph& Mees, Klaus& Plesnila, Nikolaus& Canis, Martin& Strieth, Sebastian…[et al.]. Diagnostic Potential of Distortion Product Otoacoustic Emissions in Noninvasive Assessment of Elevated Intracranial Pressure : Different Patterns of DPOAE Alterations in the Guinea Pig. ISRN Anesthesiology. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-483843
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483843