Reelin in the Years : Controlling Neuronal Migration and Maturation in the Mammalian Brain

Author

D'Arcangelo, Gabriella

Source

Advances in Neuroscience

Issue

Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-19, 19 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2014-01-09

Country of Publication

Egypt

No. of Pages

19

Main Subjects

Biology
Diseases

Abstract EN

The extracellular protein Reelin was initially identified as an essential factor in the control of neuronal migration and layer formation in the developing mammalian brain.

In the years following its discovery, however, it became clear that Reelin is a multifunctional protein that controls not only the positioning of neurons in the developing brain, but also their growth, maturation, and synaptic activity in the adult brain.

In this review, we will highlight the major discoveries of the biological activities of Reelin and the underlying molecular mechanisms that affect the development and function of the mammalian brain, from embryonic ages to adulthood.

American Psychological Association (APA)

D'Arcangelo, Gabriella. 2014. Reelin in the Years : Controlling Neuronal Migration and Maturation in the Mammalian Brain. Advances in Neuroscience،Vol. 2014, no. 2014, pp.1-19.
https://search.emarefa.net/detail/BIM-483898

Modern Language Association (MLA)

D'Arcangelo, Gabriella. Reelin in the Years : Controlling Neuronal Migration and Maturation in the Mammalian Brain. Advances in Neuroscience No. 2014 (2014), pp.1-19.
https://search.emarefa.net/detail/BIM-483898

American Medical Association (AMA)

D'Arcangelo, Gabriella. Reelin in the Years : Controlling Neuronal Migration and Maturation in the Mammalian Brain. Advances in Neuroscience. 2014. Vol. 2014, no. 2014, pp.1-19.
https://search.emarefa.net/detail/BIM-483898

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-483898