Human Blood-Vessel-Derived Stem Cells for Tissue Repair and Regeneration
Joint Authors
Chen, William C. W.
Corselli, Mirko
Huard, Johnny
Peault, Bruno
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-02
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Multipotent stem/progenitor cells with similar developmental potentials have been independently identified from diverse human tissue/organ cultures.
The increasing recognition of the vascular/perivascular origin of mesenchymal precursors suggested blood vessels being a systemic source of adult stem/progenitor cells.
Our group and other laboratories recently isolated multiple stem/progenitor cell subsets from blood vessels of adult human tissues.
Each of the three structural layers of blood vessels: intima, media, and adventitia has been found to include at least one precursor population, that is, myogenic endothelial cells (MECs), pericytes, and adventitial cells (ACs), respectively.
MECs and pericytes efficiently regenerate myofibers in injured and dystrophic skeletal muscles as well as improve cardiac function after myocardial infarction.
The applications of ACs in vascular remodeling and angiogenesis/vasculogenesis have been examined.
Our recent finding that MECs and pericytes can be purified from cryogenically banked human primary muscle cell culture further indicates their potential applications in personalized regenerative medicine.
American Psychological Association (APA)
Chen, William C. W.& Corselli, Mirko& Peault, Bruno& Huard, Johnny. 2012. Human Blood-Vessel-Derived Stem Cells for Tissue Repair and Regeneration. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-483905
Modern Language Association (MLA)
Chen, William C. W.…[et al.]. Human Blood-Vessel-Derived Stem Cells for Tissue Repair and Regeneration. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-483905
American Medical Association (AMA)
Chen, William C. W.& Corselli, Mirko& Peault, Bruno& Huard, Johnny. Human Blood-Vessel-Derived Stem Cells for Tissue Repair and Regeneration. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-483905
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483905